could glp-1 be the next mental health drug Ozempic Used for Treatment? Ozempic and other GLP-1 drugs

While the concept is scientifically sound, it's essential to recognize that most peptides being used clinically have not completed rigorous FDA-approval processes , and much of our understanding comes from preclinical (animal) studies or small, uncontrolled human observations

Methods Reagents and antibodies All chemicals including activity-based fluorescent probe of ubiquinone (NIR-ASM, #SCT072), menaquinone-4 (MK-4, #V9378), menaquinone-7 (MK-7, #1381119), NADH (#10128023001), and cOmplete EDTA-free protease inhibitor cocktail (#4693132001) were purchased from Sigma-Aldrich

Liu, Lactylation of PKM2 suppresses inflammatory metabolic adaptation in pro-inflammatory macrophages

Coumarins are natural inhibitors of VKORC1 found in many medicinal herbs